Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline Air Europa

The cheapest airline(s) flying from Panama City to Madrid is Air Europa.

  • Air Europa Air Europa
  • Avianca Avianca
  • Iberia Iberia
  • United Airlines United Airlines
  • Air Canada Air Canada
  • Air France Air France
  • KLM KLM
  • Turkish Airlines Turkish Airlines
  • American Airlines American Airlines
  • Copa Airlines Copa Airlines
Cheapest Month March

Travel Period: February 2025 - January 2026

The cheapest month(s) to fly from Panama City to Madrid is March.

  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
  • Oct 2025
  • Nov 2025
  • Dec 2025
  • Jan 2026
Cheapest Day of the Week Monday

The cheapest day(s) of the week to fly from Panama City to Madrid is Monday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Thu, 2 Jan, 2025

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  • Availability
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  • 18:20 PTY
    10:25 MAD
    10Hrs, 05m Direct
  • PTYPanama City Tocumen International Airport 18:20 - MAD 10:25 10h 05m Direct
  • PTYPanama City Tocumen International Airport 18:20
  • MADMadrid Barajas Airport 10:25
  • 10h 05m
  • Direct
  • Iberia (IB 258)Airbus Industrie A330 200
  • Iberia (IB 258)
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  • Airbus Industrie A330 200
  • 18:20 PTY
    10:25 MAD
    10Hrs, 05m Direct
  • PTYPanama City Tocumen International Airport 18:20 - MAD 10:25 10h 05m Direct
  • PTYPanama City Tocumen International Airport 18:20
  • MADMadrid Barajas Airport 10:25
  • 10h 05m
  • Direct
  • Iberia (IB 258)Airbus
  • Iberia (IB 258)
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  • Airbus
  • 03:19 PTY
    22:35 MAD
    13Hrs, 16m 1 Stop (BOG)
  • PTYPanama City Tocumen International Airport 03:19 - MAD 22:35 13h 16m 1 Stop (BOG) Bogota
  • PTYPanama City Tocumen International Airport 03:19
    BOGBogota Airport 07:00
  • BOGBogota Airport 04:54
    MADMadrid Barajas Airport 22:35
  • 13h 16m (2h 06m)
  • 1 Stop BOG · Bogota 2h 06m
  • Avianca (AV 41)Airbus
    Avianca (AV 46)Boeing 787 8
  • Avianca (AV 41)
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    • S
  • 10:00 PTY
    09:15 MAD
    17Hrs, 15m 1 Stop (EWR)
  • PTYPanama City Tocumen International Airport 10:00 - MAD 09:15 17h 15m 1 Stop (EWR) New York City
  • PTYPanama City Tocumen International Airport 10:00
    EWRNewark Liberty International Airport 19:50
  • EWRNewark Liberty International Airport 15:17
    MADMadrid Barajas Airport 09:15
  • 17h 15m (4h 33m)
  • 1 Stop EWR · New York City 4h 33m
  • United Airlines (UA 727)Boeing 737 900
    United Airlines (UA 51)Boeing 767 400
  • United Airlines (UA 727)
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  • 10:00 PTY
    09:15 MAD
    17Hrs, 15m 1 Stop (EWR)
  • PTYPanama City Tocumen International Airport 10:00 - MAD 09:15 17h 15m 1 Stop (EWR) New York City
  • PTYPanama City Tocumen International Airport 10:00
    EWRNewark Liberty International Airport 19:50
  • EWRNewark Liberty International Airport 15:17
    MADMadrid Barajas Airport 09:15
  • 17h 15m (4h 33m)
  • 1 Stop EWR · New York City 4h 33m
  • United Airlines (UA 727)Boeing 737 Max 9 Passenger
    United Airlines (UA 51)Boeing 767 400
  • United Airlines (UA 727)
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  • 17:25 BOG
    12:30 MDE
    15Hrs, 35m 1 Stop (MAD)
  • BOGBogota Airport 17:25 - MDE 12:30 15h 35m 1 Stop (MAD) Madrid
  • BOGBogota Airport 17:25
    PTYPanama City Tocumen International Airport 11:20
  • MADMadrid Barajas Airport 08:55
    MDEMedellin Jose Maria Cordova Intl Airport 12:30
  • 15h 35m (3h 57m)
  • 1 Stop MAD · Madrid 3h 57m
  • Avianca (AV 182)Boeing 787 8
    Avianca (AV 323)Airbus
  • Avianca (AV 182)
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    • -
  • 11:25 PTY
    06:30 MAD
    13Hrs, 05m 1 Stop (BOG)
  • PTYPanama City Tocumen International Airport 11:25 - MAD 06:30 13h 05m 1 Stop (BOG) Bogota
  • PTYPanama City Tocumen International Airport 11:25
    BOGBogota Airport 14:55
  • BOGBogota Airport 13:00
    MADMadrid Barajas Airport 06:30
  • 13h 05m (1h 55m)
  • 1 Stop BOG · Bogota 1h 55m
  • Avianca (AV 8383)Airbus
    Avianca (AV 26)Boeing 787 8
  • Avianca (AV 8383)
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  • 11:25 PTY
    06:30 MAD
    13Hrs, 05m 1 Stop (BOG)
  • PTYPanama City Tocumen International Airport 11:25 - MAD 06:30 13h 05m 1 Stop (BOG) Bogota
  • PTYPanama City Tocumen International Airport 11:25
    BOGBogota Airport 14:55
  • BOGBogota Airport 13:00
    MADMadrid Barajas Airport 06:30
  • 13h 05m (1h 55m)
  • 1 Stop BOG · Bogota 1h 55m
  • Avianca (AV 59)Airbus A320 Neo
    Avianca (AV 26)Boeing 787 8
  • Avianca (AV 59)
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  • 11:25 PTY
    08:55 MAD
    15Hrs, 30m 1 Stop (BOG)
  • PTYPanama City Tocumen International Airport 11:25 - MAD 08:55 15h 30m 1 Stop (BOG) Bogota
  • PTYPanama City Tocumen International Airport 11:25
    BOGBogota Airport 17:25
  • BOGBogota Airport 13:00
    MADMadrid Barajas Airport 08:55
  • 15h 30m (4h 25m)
  • 1 Stop BOG · Bogota 4h 25m
  • Avianca (AV 59)Airbus A320 Neo
    Avianca (AV 182)Boeing 787 8
  • Avianca (AV 59)
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  • 11:25 PTY
    08:55 MAD
    15Hrs, 30m 1 Stop (BOG)
  • PTYPanama City Tocumen International Airport 11:25 - MAD 08:55 15h 30m 1 Stop (BOG) Bogota
  • PTYPanama City Tocumen International Airport 11:25
    BOGBogota Airport 17:25
  • BOGBogota Airport 13:00
    MADMadrid Barajas Airport 08:55
  • 15h 30m (4h 25m)
  • 1 Stop BOG · Bogota 4h 25m
  • Avianca (AV 8383)Airbus
    Avianca (AV 182)Boeing 787 8
  • Avianca (AV 8383)
    • M
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  • 21:55 BOG
    16:44 MDE
    15Hrs, 51m 1 Stop (MAD)
  • BOGBogota Airport 21:55 - MDE 16:44 15h 51m 1 Stop (MAD) Madrid
  • BOGBogota Airport 21:55
    PTYPanama City Tocumen International Airport 15:34
  • MADMadrid Barajas Airport 13:25
    MDEMedellin Jose Maria Cordova Intl Airport 16:44
  • 15h 51m (4h 14m)
  • 1 Stop MAD · Madrid 4h 14m
  • Avianca (AV 10)Boeing 787 8
    Avianca (AV 317)Airbus
  • Avianca (AV 10)
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    • S
  • 21:55 BOG
    16:44 MDE
    15Hrs, 51m 1 Stop (MAD)
  • BOGBogota Airport 21:55 - MDE 16:44 15h 51m 1 Stop (MAD) Madrid
  • BOGBogota Airport 21:55
    PTYPanama City Tocumen International Airport 15:34
  • MADMadrid Barajas Airport 13:25
    MDEMedellin Jose Maria Cordova Intl Airport 16:44
  • 15h 51m (4h 16m)
  • 1 Stop MAD · Madrid 4h 16m
  • Avianca (AV 10)Boeing 787 8
    Avianca (AV 317)Airbus
  • Avianca (AV 10)
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  • 15:34 PTY
    13:50 MAD
    16Hrs, 16m 1 Stop (MDE)
  • PTYPanama City Tocumen International Airport 15:34 - MAD 13:50 16h 16m 1 Stop (MDE) Medellin
  • PTYPanama City Tocumen International Airport 15:34
    MDEMedellin Jose Maria Cordova Intl Airport 22:10
  • MDEMedellin Jose Maria Cordova Intl Airport 16:44
    MADMadrid Barajas Airport 13:50
  • 16h 16m (5h 26m)
  • 1 Stop MDE · Medellin 5h 26m
  • Avianca (AV 317)Airbus
    Avianca (AV 16)Boeing 787 8
  • Avianca (AV 317)
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  • 21:55 BOG
    16:44 MDE
    15Hrs, 51m 1 Stop (MAD)
  • BOGBogota Airport 21:55 - MDE 16:44 15h 51m 1 Stop (MAD) Madrid
  • BOGBogota Airport 21:55
    PTYPanama City Tocumen International Airport 15:34
  • MADMadrid Barajas Airport 13:25
    MDEMedellin Jose Maria Cordova Intl Airport 16:44
  • 15h 51m (4h 14m)
  • 1 Stop MAD · Madrid 4h 14m
  • Avianca (AV 10)Boeing 787 8
    Avianca (AV 317)Airbus
  • Avianca (AV 10)
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  • 17:25 PTY
    13:25 MAD
    14Hrs, 00m 1 Stop (BOG)
  • PTYPanama City Tocumen International Airport 17:25 - MAD 13:25 14h 1 Stop (BOG) Bogota
  • PTYPanama City Tocumen International Airport 17:25
    BOGBogota Airport 21:55
  • BOGBogota Airport 18:55
    MADMadrid Barajas Airport 13:25
  • 14h (3h)
  • 1 Stop BOG · Bogota 3h
  • Avianca (AV 61)Airbus
    Avianca (AV 10)Boeing 787 8
  • Avianca (AV 61)
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    • -
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    • -
  • 18:30 PTY
    13:25 MAD
    12Hrs, 55m 1 Stop (BOG)
  • PTYPanama City Tocumen International Airport 18:30 - MAD 13:25 12h 55m 1 Stop (BOG) Bogota
  • PTYPanama City Tocumen International Airport 18:30
    BOGBogota Airport 21:55
  • BOGBogota Airport 20:00
    MADMadrid Barajas Airport 13:25
  • 12h 55m (1h 55m)
  • 1 Stop BOG · Bogota 1h 55m
  • Avianca (AV 89)Airbus
    Avianca (AV 10)Boeing 787 8
  • Avianca (AV 89)
    • M
    • -
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  • 18:45 PTY
    16:05 MAD
    15Hrs, 20m 1 Stop (AMS)
  • PTYPanama City Tocumen International Airport 18:45 - MAD 16:05 15h 20m 1 Stop (AMS) Amsterdam
  • PTYPanama City Tocumen International Airport 18:45
    AMSAmsterdam Airport 13:30
  • AMSAmsterdam Airport 11:05
    MADMadrid Barajas Airport 16:05
  • 15h 20m (2h 25m)
  • 1 Stop AMS · Amsterdam 2h 25m
  • KLM (KL 758)Boeing Dreamliner Series 10
    KLM (KL 1505)Boeing 737 800
  • KLM (KL 758)
    • -
    • -
    • -
    • -
    • -
    • S
    • -
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What’s the fastest flight time from Panama City to Madrid?

The fastest flight time for direct flights from Panama City to Madrid is 10 hours 5 minutes. Check latest flight schedules & prices on Wego.

What’s the most popular airline flying from Panama City to Madrid?

The most popular airline flying from Panama City to Madrid is Air Europa. Find the latest flight deals on Wego.

How far is Madrid from Panama City?

The flight distance between Panama City and Madrid is 8163km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 03:19. The last flight of the day departs at 03:19. See the full list of flight times on Wego.

How many airlines offer direct flights from Panama City to Madrid?

There are 1 airlines that offer direct flights from Panama City to Madrid. Find out the list of airlines on Wego.